Descovy vs Truvada: Know More Overall, at 48 weeks, Descovy was associated with more favourable changes in eGFR and markers of proximal tubular function compared with Truvada, and proteinuria (protein in the urine) was less common (24% vs 21%, respectively), Dr Mills reported. Go to: https://www.medsengage.com/blog/descovy-vs-truvada/