What causes fulminant decrease in Platelets in Dengue? Our blood contains of red blood cells, white blood cells, platelets and plasma. The operate of platelets is to repair the vessels that puncture or tear, so the blood doesn't ‘leak out’. they are doing this by forming a mesh kind structure over the broken vessel and retain the blood to flow inside the vessel itself. consider it as however you seal a pipe by applying associate epoxy. Upon noticing a tear, they get ‘activated’ and begin forming a mesh. Once someone is littered with a breakbone fever virus, the platelets will now not ‘activate’ itself. therefore whenever there's harm, the platelets cannot type the mesh structure and therefore the blood flows out of the vessel. As blood flows out, therefore will the platelets. This causes the blood platelet count to fall drastically. The blood that flows out causes internal and external hurt and results in a hemorrhage.