Blood The blood is the attendant to transport the food and the oxygen to the cells, and to withdraw of them the products of waste. Besides it has an important paper in the immunity and the coagulation. The alterations of his components originate diverse illnesses that explain in this section. The problems of the blood affect one or several parts of this and prevent that it fulfil his function. They can be chronic or treble. A lot of blood disorders are hereditary. Other causes can be other illnesses, secondary effects of some medicine and the fault of some nutrients in the diet. Some types of problems of the blood are: • Problems plaquetarios, excessive coagulation and other problems of sangrado, that affect the coagulation • Anaemia, that occurs when the blood does not carry sufficient oxygen to his body • Blood cancers like the leukaemia, and the myeloma • Disorders eosinofílicos, that are problems with a type of white globules. Talasemia It is a very heterogeneous group of hereditary anaemias characterised by the decrease or total absence of the synthesis of one or several chains of the hemoglobin. Talasemia Greater (inherit the two copies of the gene with an important alteration in each copy or allele). - Talasemia Intermediate (inherit two copies with two moderate alterations or an important alteration and a moderate). - Talasemia minor (Also known like shot talasémico, presents if one receives the defective gene of only one of the parents. The people with this form of the disorder are bearers of the illness and regularly do not have symptoms. Factors of risk - The people that have talasemia slight beta have 50% of probabilities to transmit them the gene to his children. - Another factor of risk is to be of etnia afroamericana, Asian, Chinese or Mediterranean. Hemophilia: The Hemophilia is a coagulopatía congenital, that is to say, a disorder of the congenital and hereditary coagulation. The consequence of this defect is the synthesis of some determinate factors of coagulation. The fundamental symptom of this disorder of the coagulation is the bleeding. One of the characteristics of this bleeding is that it always is consecutive to a traumatism However, where with greater frequency produce these bleedings is in the device locomotor, in the articulations. Hemophilia is a genetic illness recesiva that prevents the good coagulation of the blood. It is related with the chromosome X and exist three types: the hemophilia To, when there is a deficit of the factor VIII of coagulation, the hemophilia B, when there is a deficit of the factor IX of coagulation, and the hemophilia C, that is the deficit of the factor XI. CORONARY THROMBOSIS • The thrombosis is a clot in the interior of a blood vessel and one of the causantes of an acute infarct of myocardium. Also it designates like this to the own pathological process, in which, an aggregated of platelets or fibrin ocluye a blood vessel. The thrombus is a mass that forms in the interior of the separate circulatory and is constituted by the blood of the patient, specifically by the solid elements of the blood. In an individual live the blood can congeal but this is out of the circulatory device for example, the blood that happens to the peritoneum, to the pleura or to the pericardium. Here the blood congeals and is not a thrombus, because it is out of the cardiovascular device. The causes are: alteration in the blood vessels; arteriosclerosis traumatic split alteration in the factors of the coagulation; thrombin, prothrombin decrease of the Protein C, Protein S, called these last trombofilias. The mechanisms that favour the training of a thrombus, are the alterations of the blood flow and these alterations can be due to excessive rest in bed (patients postoperados). Besides in the surgical intervention there has been a stimulation of the factors of coagulation by the break of glasses, the suture, a series of interventions that involve to the vascular device. It is not rare that an individual operate of a hernia inguinal, and in the moment that gives him of high and begins to move more than what has moved in the present previous days an embolism fulminante ocasionándole the death. • The third cause that influences are the components of the blood. When the blood is denser diminish the liquids and increase the elements appeared. Or there is a hemoconcentración or a real polycythemia. Inside this includes the thromboses to repetition. The places of training of thrombus are in the heart, arteries, veins and capilares, by what the thrombosis can form in any part of the circulatory device. Other pathologies that can cause a thrombosis are those that present flows in eddies, like the narrownesses valvulares. An example is the estenosis mitral, in where the flow in the auricula does slower and favours the thrombosis. In the estenosis mitral it is necessary to take into account that the most likely is that there is thrombosis in the orejuela and in some part of the wall of the auricula. And if that does flutter or fibrillation, the contraction of the auricula is ineficiente. Then the auricula does not contract and besides exists occlusion in the exit, of such way that there is a slowness of the flow of exit and therefore training of clots (thrombuses). Another cause of thrombosis is the damage of the endothelium. If a glass inflames , for example a vein of the EEII by a trauma, produces an injury of the vecindad and damage endotelial, that unchains immediately the waterfall of coagulation depositing thrombuses in the surface of the glass. Anaemia • The anaemia, or decrease of the concentration of hemoglobin in the blood, can be due to diverse causes, and the most common is the fault of iron, but also can be a symptom of an underlying disorder. • High incidence in boys, women, young or subject adults with lacks in his feeding (deficit of iron and sour fólico, especially). • It is used to to be associated to many other pathologies, in which it constitutes a symptom of the underlying disorder. • High frequency in some ethnic groups (related with the malnutrición and very widespread, therefore, in those countries in roads of development, whose population lacks resources to keep a suitable feeding). Adaptation of the system cardiocirculatorio. In front of an anaemia, the organism answers of immediate form with a redistribution of the blood, whose aim is to guarantee the oxygenation of the vital organs. In this process produce two simultaneous phenomena: Redistribution of the blood flow In the phenomenon of redistribution produces a vasoconstricción of the less needy areas, for example, the skin (paleness) and the kidney, to derive the blood to regions more critical, for example, the brain. That is to say, the blood vessels of organs less important close and the blood that can not go through they diverts to go through others of organs more important. Increase of the cardiac debit The greater debit or cardiac cost is an answer to the hypoxia of the fabrics; that is to say, it increases the quantity of blood pumped by the heart. This phenomenon does not develop until the concentration of hemoglobin in blood descends underneath of 70 g/L. Clinically, the greater cardiac debit self-evident with taquicardia and apparition of soplos sistólicos functional (produced by the blood when going out of the heart without that there is any pathology in the cardiac structures). If the anaemia is very intense and of brusque instauration (acute anaemia), the decrease of the venous pressure can facilitate the apparition of a shock hipovolémico. By the contrary, when it is of slow instauration (chronic anaemia), exists a progressive and characteristic increase of the volume plasmático to keep the volemie and avoid the apparition of the shock. Proofs of laboratory To confirm the diagnostic of anaemia is precise to show first the descent of the concentration of hemoglobin in blood. For this makes an analysis of blood, called hemogram, that determines the levels of hemoglobin in the blood together with other parameters that indicate the morphology and size of the hematíes. Besides, the hemogram informs us of possible alterations in other blood cells as they are the white globules and the platelets. The treatment of the anaemia depends on the cause that causes it. It was cual was, the aim will be to increase the level of oxygen that the blood is able to transport, already was by means of the increase of red globules or the concentration of hemoglobin. Of course, it will be necessary to treat also the cause or illness that can have caused the anaemia. In general it will suffice with the replacement of iron by oral road in cases of anaemia ferropénica; or of vitamin B12 and sour fólico in cases of anaemia megaloblástica. When it was due to important losses of blood will make a transfusion of blood. And in cases more specific (like hereditary syndromes) can pose the transplantation of osseous marrow. Anyway it is necessary to consult with the medical specialist so that it indicate you the treatment of the most adapted anaemia for your case. With their help of 0.00001 btc I would be helping to continue to publish reports to the network I am waiting for your help, thank you very much