We're still 5 days away from the next difficulty adjustment
 but at the moment the estimate is nearly 10 million higher
 than the last adjustment (now 45.9 million). With an
 estimate of 47.3 million difficulty my Januaray Jalapeno
 pre-order will be hashing the same amount of bitcoin per
 day as my 7870 was when I ordered it.

I think it's pretty fair to say that GPU mining is nearly done
 across the board. Unless you don't pay for power, your
 power costs are very low or you just don't care mining by
 GPU is almost at negative income. Even Blockchain
 estimates miner's operating margins at around -50%(http://blockchain.info/charts/miners-operating-profit-margin)�
Needless to say we can easily expect difficulty to reach
around 100 million by October