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The present application refers to methods for cancer diagnosis and treatment, particularly in types of cancers associated with aberrant CpG methylation of the miR-34a
Results Hypermethylation of miR-34a promoter in Kazakh patients with ESCC The MassARRAY system is a tool for the high-throughput detection and quantitative analysis
TP53 and MGMT function is affected by several pathologic mechanisms, such as point mutations or promoter methylation, MiR-21, miR-34a, miR-125b,
Regulation of miR-34 by promoter methylation and copy number alterations Promoters of both mir-34a and mir-34b*/c are located in CpG islands and methylation has
No significant differences in expression of miR-34 family members were detected among different histologic types of mir-34a promoter methylation, and/or copy
miR-34a/SIRT1/p53 is suppressed by ursodeoxycholic acid in the rat liver and activated by disease severity in human non-alcoholic fatty liver disease
A biweekly scientific journal publishing high-quality research in molecular biology and genetics, cancer biology, biochemistry, and related fields
Synthetic miR-34a Mimics as a Novel Therapeutic Agent for Multiple Myeloma: hypermethylation of miR-34a promoter has been found in MM patient cells and MM cell
Anti-NF?B p50 Antibody is a Rabbit Polyclonal Antibody for detection of NF?B p50 also known as DNA-binding factor KBF1, nuclear factor NF-kappa-B p50 subunit & has
Cell death and differentiation is a monthly research journal focused on the exciting field of programmed cell death and apoptosis. It provides a single accessible
Contract Assay Services; Search results for: '19154' You searched for: 19154. in the intronic promoter of MDM2 and miR-34a expression.
Contract Assay Services; Search results for: '19154' You searched for: 19154. in the intronic promoter of MDM2 and miR-34a expression.
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Here we report that microRNA-34a (miR-34a) functions as a novel node in the squamous cell differentiation network, miR-34a promoter sequences
Ectopic expression of miR-34a, but not miR-34b/c, increases p53 transcriptional activity. To assess the effect of miR-34a on the p53 response, we used qRT-PCR to
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