Marvel counts among its characters such well-known superheroes as Captain America, Iron Man, Hulk, Thor, Doctor Strange, Spider-Man, Wolverine and Ant-Man, such teams as the Avengers, the Guardians of the Galaxy, the Fantastic Four, the Defenders, the X-Men and the Inhumans, and antagonists such as Doctor Doom, Red Skull, Green Goblin, Ultron, Doctor Octopus, Thanos, Magneto and Loki. Most of Marvel's fictional characters operate in a single reality known as the Marvel Universe, with locations that mirror real-life cities. Characters such as Spider-Man, the Fantastic Four, the Avengers, Daredevil and Doctor Strange are based in New York City,[1][2] whereas the X-Men have historically been based in Salem Center, New York[3][4][5] and Hulk's stories often have been set in the American Southwest.[6]