Some people still like to get general stuff for mining purpose, or cheap rendering.
How to do these heavy jobs?
You have one x16 and one x1. But you have two x16 GPU.
To do, Simply use something called x1m to x16f convertor (https://bitcointalk.org/index.php?topic=247167.5;wap2, http://www.hkepc.com/forum/viewthread.php?tid=1943790 ) to connect one of two x16 GPU.
After that, Except Gaming, the other purpose is okay, just slow preparation speed on one of the GPUs.
To check, simple ask PCI-E standard note, they say almost everything.