Femme cherche homme annonces ocp ocp


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  7. In a recent meta-analysis, levels of ovulation in women taking low-oestrogen 20 microgram formulations of levonorgestrel COCs were shown to be similar to those in women taking standard-dose 30 microgram formulations Table 1. Table 1 Incidence of ovulation in women taking levonorgestrel COCs Oestrogen dose % ovulation rate 95% confidence interval 20 micrograms 8. Headache is reported to be a very common side effect associated with use of low-oestrogen formulations of levonorgestrel COCs. Some women who are particularly sensitive to oestrogen levels may therefore find the lower ethinyloestradiol dose beneficial. Such formulations are associated with an increased risk of bleeding disturbances amenorrhoea or infrequent bleeding, break-through bleeding or spotting, or irregular, prolonged frequent bleeding compared with higher-ethinyloestradiol-dose COC formulations. While this bleeding is not a threat to a woman's health it can reduce acceptance and adherence to the contraceptive. Venous thromboembolism VTE is a rare side affect associated with use of all COCs. The risk is dependent on the dose of oestrogen, the progestogen used and the presence of other risk factors. Reducing the oestrogen dose of COCs from 30 micrograms or 30—40 micrograms to 20 micrograms reduced the risk of VTE in three recent studies. The authors suggested that the study was underpowered to determine a difference in VTE risk between these doses. The risk of cardiovascular complications from COCs is well established. Take a thorough medical history before prescribing any COC to identify contraindications. Do not prescribe COCs for women with cardiovascular risk factors, including prior VTE. When choosing a COC, select one that has the lowest effective dose of oestrogen and progestin, is well tolerated and provides acceptable cycle control with the least known effect on carbohydrate or lipid metabolism and haemostatic parameters. As reducing the oestrogen dose of COCs can reduce risk of VTE, levonorgestrel COCs with standard oestrogen dose 30—35 micrograms or low oestrogen dose 20 micrograms may be suitable for women requiring contraception but who have other risk factors for VTE but not contraindications. Refer women with a family history of VTE to a specialist. Date published: 4 April 2013 Reasonable care is taken to provide accurate information at the time of creation. This information is not intended as a substitute for medical advice and should not be exclusively relied on to manage or diagnose a medical condition. NPS MedicineWise disclaims all liability including for negligence for any loss, damage or injury resulting from reliance on or use of this information. This website uses cookies.

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